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Leftover Pot Roast Patty Melts

4.5 from 128 votes
With a creamy mayo-steak sauce spread, grilled onions, and two kinds of cheese, you'll love these leftovers!
photo of Danelle, author of Let's Dish
Published on , Updated October 22, 2025
4.5 from 128 votes
Leftover Pot Roast Patty Melts

The Best Thing to Happen to Leftover Pot Roast

These patty melts turn last night’s pot roast into crispy, melty magic. With caramelized onions, two kinds of cheese, and a creamy sauce that pulls it all together, they’re everything you want in a hot sandwich—no one will even guess it started as leftovers.

Here’s why you’ll love it:

  • Perfect use for leftover pot roast
  • That dreamy sauce—just mayo and steak sauce, but it makes the sandwich
  • Crispy on the outside, gooey on the inside
  • Totally customizable with whatever cheese or bread you’ve got
  • Comfort food vibes in under 30 minutes

Believe me when I say that this sandwich is the epitome of diner-style comfort food. I highly recommend some French fries or a bowl of Creamy Tomato Parmesan Soup.

Leftover Pot Roast Patty Melts

Leftover Pot Roast Patty Melts

With a creamy mayo-steak sauce spread, grilled onions, and two kinds of cheese, you'll love these leftovers!
4.48 from 128 votes
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Course: Main Dishes
Cuisine: American
Prep Time: 15 minutes
Cook Time: 10 minutes
Total Time: 25 minutes
Servings: 4 -6 servings
Calories: 779kcal
Author: Danelle

Ingredients 

For the sandwiches:

  • 2-3 cups leftover shredded pot roast
  • 8 slices sturdy bread
  • 3 tablespoons butter plus more for the bread
  • 2 medium onions thinly sliced
  • Salt and pepper to taste
  • 4 slices Provolone cheese
  • 4 slices cheddar cheese

For the sauce:

  • 1/2 cup mayonnaise
  • 3 tablespoons steak sauce
  • 1/8 teaspoon pepper

Instructions

  • Re-heat the pot roast in the microwave. Butter one side of all 8 slices of bread.
  • Melt 3 tablespoons of butter in a large skillet. Add onions and cook over medium heat, stirring frequently, until onions are soft and golden brown.
  • Season with salt and pepper and remove from heat.
  • Combine the sauce ingredients in a medium bowl.
  • Heat a griddle over medium-high heat. Spread a layer of the sauce on the unbuttered side of 4 slices of bread. Top with a piece of cheddar cheese.
  • Top each slice of cheddar with about 1/2 cup of pot roast, a generous portion of onions, and the slice of Provolone cheese. Top with the remaining slice of bread, buttered side out.
  • Grill, flipping once, until both sides are browned and crispy.
  • Serve patty melts with the remaining sauce, for dipping.

Nutrition

Serving: 1g | Calories: 779kcal | Carbohydrates: 35g | Protein: 41g | Fat: 51g | Saturated Fat: 20g | Polyunsaturated Fat: 28g | Trans Fat: 1g | Cholesterol: 141mg | Sodium: 826mg | Fiber: 3g | Sugar: 8g
Keep scrolling for tips, ingredient substitutions, answers to frequently asked questions and more!
Leftover Pot Roast Patty Melts

Here’s how to make sure your patty melts turn out perfectly:

Recipe tips icon

Recipe Tips

  • Butter matters: Spread it evenly to get a golden crust all the way to the edges.
  • Don’t rush the onions: They’re the soul of the sandwich—deep flavor comes from slow cooking.
  • Don’t overload: Too much filling makes flipping messy. Keep it hearty, but balanced.
  • Use a press or skillet weight if you want an extra crispy finish (and more diner-style vibes).

Leftovers, Again?

These sandwiches are best hot off the griddle, but here’s how to make them work for later:

  • Prep ahead: Caramelize onions and mix the sauce in advance. Store separately in the fridge.
  • Reheat gently: Leftovers can be crisped back up in a pan over low heat or in a toaster oven. Avoid microwaving—it’ll soften the bread.

Switch Things Up

A few easy variations can give this sandwich a new spin every time:

  • Try a different sauce: BBQ mayo, garlic aioli, or even horseradish cream.
  • Go veggie-friendly: Swap in roasted mushrooms or sautéed peppers.
  • Change the bread: Texas toast, rye, or even focaccia would be delicious.

The grilled onions are the star of these sandwiches, as far as I’m concerned. Sure, it takes a little bit of time and attention to get them caramelized just right. But it’s SO worth it!

Be sure to save this recipe to your favorite Pinterest board for later.

Leftover Pot Roast Patty Melts

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4.48 from 128 votes (128 ratings without comment)

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photo of Danelle, author of Let's Dish

Hello! I’m Danelle. Thanks for visiting.

At Let's Dish, I'm bringing a taste of uptown foodie to real-life, everyday meals! Here, I share simple, reliable recipes that make mealtime easy.
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